General Cell Lines and Cell Cultures
Amsbio LLC eLuCidate™ HEK 293, TCF/LEF Reporter Cell Line
eLuCidate™ HEK 293 TCF/LEF Reporter Cell Line
Eurofins Discoverx ChemiScreen GPR109A Nicotinic Acid Receptor Stable Cell Line, 2 vials. (HTS201C)
The ChemiScreen GPR109A Nicotinic Acid Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. nicotinic acid) based activation of HCAR2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses HCAR2 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of HCAR2, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Cell Systems Corporation Primary Human Lung Fibroblast Cells (ACBRI 469 V)
Primary Human Lung Fibroblast (ACBRI 469 V) were initiated from normal human lung tissue. Unlike cells from other providers, Cell Systems primary cells are isolated without antibody labels for enhanced biological relevance. Each vial contains ~1 x 10^6 cells with 85-92% viability under ideal conditions. They are available at Passage 3 (<12 cumulative population doublings) and will initiate a Passage 4 cell culture in a 75 cm2 flask. Each vial of cells is shipped with Bac-Off (antibiotic) and CultureBoost (animal derived growth factors) at no additional cost. You can enhance consistency in your research program with reserved lots. Need vials in bulk? Contact your Fisher Scientific Sales representative for tailored quotes. Tight Deadline? Our cells are available for next day delivery after the purchase order is received. Accelerate Your Research! Try our Attachment Factor (4Z0-201, 4Z0-210) – innovative 5 seconds plating solution for all surfaces.
Cayman Chemical OrexIn A PosItIve Control 10uL
A peptide increases jejunum and ileum crypt depth and villus height without disrupting gut microbiota diversity in rats at 0.9 mg/kg four days per week decreases lapatinib-induced diarrhea severity and incidence in rats prevents lapatinib-induced loss of body weight in rats
Brainxell Inc Cortical Astrocytes (Human iPSC-Derived, Male Line, 2M)
Cortical astrocytes derived from iPSC line WC-30, male. Contents: 1 vial of ≥2x10^6 viable cryopreserved cells. Marker Expression and Morphology: Cortical Astrocytes (BX-0600) express key astrocyte markers GFAP (green) at >70%. Cortical Astrocytes promote neurite outgrowth and exhibit mature process-bearing morphologies (shown with a DAPI stain). Function: Cortical Astrocytes uptake glutamate. Cortical Astrocytes exhibit calcium waves. Related diseases: Autism, Epilepsy, Alzheimer's & Huntington's Disease.
ATCC sNF02.2; NF1 Schwann-Like Cell; Human (Homo sapiens)
sNF02.2 is a Schwann cell line that was isolated in 2002 of a 35-year-old, male patient with neurofibromatosis type 1 Nf1. This cell line was deposited by DF Muir, MR Wallace and can be used in neuroscience research.
Biochain Institute Inc Frozen Tissue Section - Human Diabetic Diseased Tissue: Skeletal Muscle, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
XenoTech,LLC Pooled IGS Sprague-Dawley rat liver microsomes, male, 0.5 ML at 20 ME/ML (10 ME)
Pooled IGS Sprague-Dawley rat liver microsomes, male, 0.5 ML at 20 ME/ML (10 ME)
![ATCC Vaccinia virus; Strain: vTF7-3 [Wr]](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502384147.PNG-250.jpg)
ATCC Vaccinia virus; Strain: vTF7-3 [Wr]
Vaccinia virus strain vTF7-3 [Wr] is propagated in BS-C-1 cells (ATCC CCL-26). This strain was constructed in vitro by transfecting vaccinia virus-infected cells with pTF703 cells (ATCC 67202) and was deposited by the National Institutes of Health. It expresses bacteriophage T[7] RNA polymerase. This product requires a VS 16-6A permit, which can be downloaded at the USDA website here. Please submit the completed permit form to SalesPermits@atcc.org with your ATCC sales order number and/or your purchase number noted in the subject line and body of the email.
Sciencell Research Laboratories MOUSE ASTROCYTES
Isolated from postnatal day 2 C57BL/6 mouse brain. MA are cryopreserved as primary cultures and delivered frozen. Each vial contains >5 x 10^5 cells in 1 ml volume.
Genscript Corporation CHO-K1/NIACR1/G15 Stable Cell
Recombinant CHO-K1 cells stably overexpress human nicotinic acid receptor (NIACR1) also known as hydroxycarboxylic acid receptor 2 (HCAR2) on the surface and contain high levels of G protein G i to couple with the receptor in downstream signaling pathways
Genscript Corporation HEK293/FP/G15 Stable Cell Lin
Prostaglandin F (2-alpha) is known as a potent luteolytic agent It is involved in modulating intraocular pressure and smooth muscle contraction in uterus Its effects on cells are mediated through specific interaction with the Prostanoid receptor FP which is a 359-amino acid protein Having 7 putative transmembrane domains FP resembles the characteristic of G protein coupled receptors Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thereupon induce luteolysis
ACROBiosystems HEK293/Human STEAP1 Stable Cell Line
Six-transmembrane epithelial antigen of the prostate 1 (STEAP1) is an integral membrane protein that is highly up-regulated on the cell surface of several human cancers, making it a promising therapeutic target to manage these diseases. It shares sequence homology with three enzymes (STEAP2-STEAP4) that catalyze the NADPH-dependent reduction of iron(III). Taking into account its high specificity and overexpression in human cancers, STEAP1 is nowadays a promising candidate to be imposed as a therapeutic target.